Dr.med. Sabine Neugebauer-Baba

Clinic

	State examination Approval Recognition as an internist Recognition as an angiologist (vascular specialist) 1987 –1993 Year 1 Year 2 Year 3 Year 4 Year 5 Year 6	5th May 1987 2nd June 1987 Januar 1997 September 2004 Medical University of Lübeck (MUZL), Internal Medicine Clinic Nephrology (kidney medicine) and rheumatology Hemodialysis, emergency services Intensive care medicine, vascular outpatient clinic, endocrinology Gastroenterology (gastrointestinal diseases) Oncology and hematology (tumor and blood diseases) Angiology and cardiology (vascular and heart diseases)
	01/1993 – 12/1999	University of Tokyo Postdoctorial Fellow Genetic research on microangiopathic complications of diabetes. PhD Degree
	01/2000 – 06/2002	Fukushima Medical University, Treatment and training of diabetics
	07/2002 – 11/2004	Dominikus Hospital Vascular Center, Düsseldorf Treatment of patients with arteriosclerosis, such as smoker's leg and stroke
	2005 -	Praxis.med. Neugebauer-Baba
	2010 -	Opening of the private medical center with Tsuneharu Baba MD. PhD, Prinzenallee 19, 40549 Düsseldorf for preventive examinations
	2014 -	Academic teaching practice at the Heinrich Heine University Düsseldorf Training of students and Authorization to continue training as a specialist in general medicine (for 2 years)

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Dr.med. Sabine Neugebauer-Baba

Research

	Doktorate	08th May 1989	Medical University of Lübeck
	Title	Development of a test strip for the detection of thyroid autoantibodies using the dot immunoassay with specially selected antigens (Dealing with the early detection of thyroid diseases)
	PhD	30th März 2001	at University of Tokyo, Tokyo, Japan
	Title	Genetic predisposition of type 2 diabetics to diabetic nephropathy and retinopathy: search for genetic markers (Dealing with the early detection and treatment of circulatory disorders in diabetics)
	Diabetes Research	1989 – 1992 1993 – 1994 1995 – 2001	Medical University of Lübeck International Medical Center and University of Tokyo, Tokyo, Japan
	Research topics	Insulin receptor signal processing, molecular biological changes and genetic background of diabetic micro- and macrovascular complications, insulin resistance and hypertension
	Research awards	Foreign Student Research Award from the University of Tokyo 11.03.1999 and 12.09.2000
	Scholarships	Grants in Aid of the Japanese Society for Health and Anti-Aging (1993) EU scholarship for the science and technology program in Japan (1995-1997)
	Memberships Academic Societies	European Association of Study of Diabetes (EASD) European Diabetic Nephropathy Study Group (EDNSG) European Study Group of Diabetes and Hypertension Japanese Diabetes Association Association of German Internists

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Dr.med. Sabine Neugebauer-Baba

International

1. Neugebauer S. Development of a test strip with specially selected antigens for the detection of thyroid autoantibodies and thyroglobulin using the dot immunoassay. Dissertation, 1989
2. Wenzel BE, Neugebauer S, Schultek T. Detection of thyroid auto-antibodies and of thyroglobulin with a new dot-ELISA method. Porceedings of the International Meeting on thyroid function and dysfunction: modern concepts. Pisa, October 2-4, 1985, pp 161-166
3. Neugebauer S, Rob PM, Schulz E. Preclinical and clinical first aid for acute kidney failure (ANV). Lübeck Emergency Symposium 1989, R18
4. Klein HH, Kowalewski B, Kotzke G, Drenckhan M, Neugebauer S, Matthaei S, Kotzke G. Decreased insulin effect on the activation of insulin receptor kinase in intact mononuclear cells from patients with non-insulin-dependent diabetes mellitus. Diabetes 42:883-890, 1993
5. Baba T, Neugebauer S. The link between insulin resistance and hypertension: effect of antihypertensive and hypolipidaemic drugs on insulin sensitivity. Drugs 47:383-404, 1994
6. Neugebauer S, Baba T, Watanabe T, Ishizaki T, Kurokawa K. The N-acetyltransferase (NAT) gene: an early risk marker for diabetic nephropa thy in Japanese Type 2 diabetic patients? Diabetic Med 11:783-788, 1994
7. Baba T, Neugebauer S, Watanabe T. Current Understanding in the Link between Hypertension and Diabetic Nephropathy and Up-to-date Pharmacological Management. Drugs 54 (2):197-234, 1997
8. Neugebauer S, Baba T, Kurokawa K, Watanabe T. Defective Homocysteine metabolism as a risk factor for diabetic retinopathy. Lancet 349:473-474, 1997
9. Neugebauer S, Baba T, Watanabe T. Inherited disorder of the homocysteine metabolism: A risk factor for end-stage diabetic nephropathy. Therapeutic Research Vol 19, 1998
10. Baba T, Drenckhan M, Neugebauer S, Klein H. Effect of angiotensin II and bradykinin on insulin-stimulated tyrosine kinase activity of insulin receptor. Diabetologia :741-742, 1998
11. Neugebauer S, Baba T, Watanabe T. Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy in NIDDM patients. Lancet 352:454, 1998
12. Neugebauer S, Baba T, Watanabe T. Nitric oxide synthase gene polymorphism is associated with an increased risk for progression to diabetic nephropathy in Type 2 Diabetes. Diabetes 49:500-503, 2000
13. Protein and gene procedures in: Laboratory techniques in renal cell and molecular biology, Editor Tomino Y, Karger, 2000
14. S. Neugebauer, L. Tarnow, C. Stehouwer, T. Teerlink, T. Baba, T. Watanabe, H.-H. Parving. Total plasma homocysteine as determinant for hypertension: Missing link between moderate hyperhomocysteinemia and cardiovascular disease in Type I diabetic patients? Diabetologia 45:1315-1324, 2002

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